Skin care
Dr. Neha Shukla
MD (Gold Medalist) · Dermatologist
Medical dermatology and doctor-led aesthetic treatment — acne, hair fall and pigmentation treated as medical problems, not packages.
4.8★1,163 Google reviews
Supporting the skin's own repair process
PDRN is an injectable derived from purified salmon DNA fragments, used to support tissue repair and improve overall skin quality. It works on skin condition, not shape or volume — a different job to filler or Botox.
PDRN Therapy (Polynucleotide / Salmon DNA) — doctor-administered at the hospital
Polydeoxyribonucleotide, or PDRN, is a purified extract of DNA fragments, most commonly sourced from salmon, that is injected into the skin to support the body's own tissue-repair signalling. It is used in wound healing in other areas of medicine, and in dermatology it is used cosmetically to support skin quality — hydration, tone and a healthier-looking texture — rather than to add volume or relax muscle.
It is often grouped alongside skin boosters and exosome therapy as a 'skin quality' treatment, distinct from fillers, which restore volume, and Botox, which relaxes muscle movement. People choose it for generally tired, dull or crepey-looking skin, or alongside other procedures such as laser or microneedling to support healing.
The evidence base is genuinely growing rather than settled — reasonable data supports its use for skin hydration and repair, less for dramatic cosmetic transformation. It is offered here as a supportive skin-quality treatment with modest, realistic expectations, not a replacement for volume or muscle-relaxing treatments where those are what someone actually needs.
Packages & pricing
Session packages
Priced per session and by area treated, as a course — a single session gives a mild, temporary hydration boost rather than a lasting change in skin quality.
| Area | Course | Price |
|---|---|---|
| Under-eye area | Course of 3–4 | On request — ask on WhatsApp |
| Full face | Course of 3–4 | On request — ask on WhatsApp |
| Neck | Course of 3–4 | On request — ask on WhatsApp |
| Combined with microneedling | Per session | On request — ask on WhatsApp |
- Sessions are typically spaced two to three weeks apart for the initial course, then maintenance every few months.
- Often planned alongside other skin-quality treatments, such as skin boosters or exosome therapy, rather than in isolation.
Dermatology at this hospital is self-pay. We do not have an insurance facility for skin — neither for aesthetic treatment, which no Indian health policy covers, nor for medical dermatology consultations and courses.
Technology
How it is administered
- Purified, sterile PDRN preparation, injected in a series of fine micro-injections or with a fine cannula
- Typically placed under the eyes, across the face, or on the neck and hands depending on the concern
- Sometimes combined with microneedling to distribute it more evenly through the upper skin layers
- A course of sessions rather than a single treatment, since repair signalling builds cumulatively
- Administered by Dr. Neha Shukla, MD Dermatology
Suitability
Who this suits
- Generally dull, dehydrated or tired-looking skin without significant volume loss
- Fine crepiness and reduced skin quality, particularly under the eyes and on the neck
- Support for skin healing alongside or after laser, microneedling or other resurfacing
- People wanting a skin-quality treatment rather than a volume or muscle-relaxing one
- Not a substitute for filler where volume loss is the actual problem, or for Botox where muscle movement is the cause of lines
- Not suitable with a known allergy to fish-derived products, in pregnancy, or over active infection
The process
A session, start to finish
Assessment
Whether skin quality is genuinely the issue, or whether volume loss or muscle movement — better addressed with filler or Botox — is actually driving what you are noticing.
Numbing
About 20 minutesTopical anaesthetic on the treatment area, particularly around the eyes.
Injection
15–30 minutesFine micro-injections placed across the treatment area, or delivered with microneedling for more even distribution.
Immediately after
Small bumps and mild redness at injection points settling within hours; occasional light bruising, particularly under the eyes.
The course
Repeated across the planned sessions, with skin quality assessed between visits.
Aftercare
After a session
- No rubbing or massaging the treated area for 24 hours
- Sunscreen daily, as with any injectable procedure
- No makeup for a few hours if injection points are visible
- Mild swelling or small bumps at injection sites settle within a day
- No gym, sauna or steam for 24 hours
Next step
Ask about pdrn therapy
Two taps and your message is written. Dr. Neha's team replies with a time — in English, ગુજરાતી, हिन्दी or मराठी.
- No form to fill in and no call centre — the message goes to the hospital.
- Ask a price or check your insurance without committing to a date.
- Answered by Dr. Neha's own team, who can see your history.
Book in three taps
Tell us what it's about and we'll reply with a time.
1What is it about?
Pick what it's about and we'll write the message for you.
Questions
What people ask us
In English and ગુજરાતી, because the decision gets made in whichever one you think in.
What does PDRN actually do that a filler doesn't?PDRN ફિલરથી કઈ રીતે અલગ છે?
Filler adds volume where it has been lost. PDRN does not add volume — it is meant to support the skin's own repair processes and improve overall quality, hydration and texture. They solve different problems and are sometimes used together.
ફિલર જ્યાં વોલ્યુમ ઓછું થયું હોય ત્યાં તે ઉમેરે છે. PDRN વોલ્યુમ ઉમેરતું નથી — તે ત્વચાની પોતાની રિપેર પ્રક્રિયાને ટેકો આપી, એકંદર ગુણવત્તા, ભેજ અને ટેક્સચર સુધારવા માટે વપરાય છે. બંને અલગ સમસ્યાઓ ઉકેલે છે અને ક્યારેક સાથે પણ વાપરવામાં આવે છે.
Is PDRN well studied?
It has a longer history of use in wound healing in other areas of medicine, and a growing but still developing body of evidence for cosmetic skin-quality use. It is offered here with that honestly stated — as a supportive treatment with modest, realistic expectations, not a proven dramatic transformation.
Is it safe if I have a fish allergy?
PDRN used here is derived from purified salmon DNA. If you have a known fish allergy, this is discussed at consultation and may rule the treatment out — tell us before booking.
How many sessions before I see a difference?
Most courses run three to four sessions, a few weeks apart, before skin quality change becomes noticeable. A single session gives a mild, short-lived hydration boost rather than a lasting result.
Can this replace Botox or filler for me?
Not if lines are from muscle movement, or hollowing is from volume loss — those need Botox or filler respectively. PDRN is for overall skin condition. Which one you actually need is assessed at consultation rather than assumed.
Results & reviews
PDRN Therapy (Polynucleotide / Salmon DNA) at Eye & Skin Plus
Dr. Neha Shukla holds 4.8★ across 1,163Google reviews. Treatment-specific patient stories for this page are being recorded with patients' written consent — see patient stories.
Related at this hospital
Ask about pdrn therapy
Send us a message describing what you would like treated. Dr. Neha's team will tell you what is realistic, and what it costs.
Near Atria Mall, Sargasan Circle, Gandhinagar · Replies in English, ગુજરાતી, हिन्दी or मराठी